It is a vitamin used to treat patients with deficiencies due to increased dietary requirements, reduced intakes, reduced absorption or increased excretion. It is used as a supplement in alcholic patients.

Thiamine is mainly the transport form of the vitamin, while the active forms are phosphorylated thiamine derivatives. There are five known natural thiamine phosphate derivatives: thiamine monophosphate (ThMP), thiamine diphosphate (ThDP), also sometimes called thiamine pyrophosphate (TPP), thiamine triphosphate (ThTP), and the recently discovered adenosine thiamine triphosphate (AThTP), and adenosine thiamine diphosphate. Each derivative has unique functions, however, most are involved as coenzymes.

Restlessness, Angioneurotic edema, Nausea, Pulmonary edema, , Gi bleeding, Pruritis, Hemorrhage, Urticaria, Cyanosis

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