Disulfiram is used to discourage drinking in?patients with chronic alcoholism. This medicine can help in staying away from drinking?by causing unpleasant side effects, if?alcohol is consumed while taking disulfiram. These effects include flushing of the face, headache, nausea, vomiting, chest pain, weakness, blurred vision, mental confusion, sweating, choking, breathing difficulty, and anxiety. These effects begin about 10 minutes after alcohol enters the body and last for 1 hour or more. Disulfiram is not a cure for alcoholism, but discourages drinking.

Disulfiram belongs to a family of medicines called aldehyde dehydrogenase inhibitors. When alcohol is consumed, it is converted into a chemical called aldehyde by natural breakdown process, this chemical is further broken down by the chemical (enzyme) aldehyde dehydrogenase thereby allowing alcohol to be excreted. Disulfiram stops this enzyme aldehyde dehydrogenase causing an increase in the blood levels of aldehydes. As a result, the person on alcohol gets very unpleasant reactions (also known as aldehyde syndrome) such as flushing, burning sensation, throbbing headache, perspiration, uneasiness, tightness in chest, dizziness, vomiting, visual disturbances, mental confusion, postural fainting and circulatory collapse which last for nearly 1-4 hours (depending upon the quantity of alcohol intake). Sensitivity to alcohol is developed which lasts for a long period of time, as a result the person experiences unpleasant reactions upon consuming alcohol even days after stopping disulfiram.

Paranoia, Respiratory depression, Itching of skin, Pyschotic disorders such as depression, St depression, Bad breath, Allergic dermatitis.disulfiram-alcohol reaction characterized by flushing, Blurred vision, Inflammation of nerves, Raised, Qt prolongation, Sweating, Breathlessness, Damage to liver cells, Vomiting, Drowsiness, Low blood pressure, Inflammation of the liver, Urge to vomit, Liver failure, Schizophrenia, Loss of sex drive, Pale red, Coma and fits ., Inflammation of the optic nerve, Dizziness, Chest pain, Anxiety, Irregular heart rhythm, Rapid heartbeat and hyperventilation.severe reactions are characterized by increased heart beat, Encephalopathy, Headache, Increased body temperature, Itchy skin rash, Mania

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