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Gabapentin is used to treat fits (epilepsy), long standing?pain in legs and/or arms caused by damage to the nerves (peripheral neuropathic pain) and disease of trigeminal nerve (trigeminal neuralgia).

The exact mechanism of action is unknown; however, gabapentin treats fits (epilepsy by decreasing abnormal excitement in the brain. It also relieves the pain of peripheral neuropathic pain by changing the way the body senses pain.

Aggression, Behavioural changes, Somnolence, Dizziness, Nystagmus, Euphoria, As well as weight gain, Fatigue.


Pyridoxine is used to treat low levels or deficiency of vitamin B6 in the body, treat nerve damage (peripheral neuritis) caused by isoniazid (an anti-tuberculosis drug), urge to vomit (nausea) and vomiting in pregnancy, and abnormal blood cells produced by bone marrow (idiopathic sideroblastic anemia). It is used for the growth and development of the brain, nerves, skin, and other parts of the body.

Pyridoxine is vitamin B6, required for the proper usage of nutrients and production of energy in the body.

Usually in hands and feet., Long term administration of large doses is associated with dysfunction of nerves resulting in numbness and pain


It is a vitamin used to treat patients with deficiencies due to increased dietary requirements, reduced intakes, reduced absorption or increased excretion. It is used as a supplement in alcholic patients.

Thiamine is mainly the transport form of the vitamin, while the active forms are phosphorylated thiamine derivatives. There are five known natural thiamine phosphate derivatives: thiamine monophosphate (ThMP), thiamine diphosphate (ThDP), also sometimes called thiamine pyrophosphate (TPP), thiamine triphosphate (ThTP), and the recently discovered adenosine thiamine triphosphate (AThTP), and adenosine thiamine diphosphate. Each derivative has unique functions, however, most are involved as coenzymes.

Restlessness, Angioneurotic edema, Nausea, Pulmonary edema, , Gi bleeding, Pruritis, Hemorrhage, Urticaria, Cyanosis

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